LIS2DH12TR Power consumption is 500uA. I have attached the Schematic and PCB file. Could you possible to suggest the power reduction in hardware or firmware level.

[AMOHA.2]

[AMOHA.2]

How Can I resolve above issues?

[Linas L]

I have similar chip and it draws 5uA.

You need to disable high resolution mode, and use low frequency update, like 100Hz or even less.

Can you read WHO_AM_I register ?

[Tesla DeLorean]

How much current is consumed by this section of the board if you remove the LIS2DH from it?

Get better at diagnostic and debugging technique?

[AMOHA.2]

Without accelerometer the board consuming 17uA. With Accelerometer 504uA. Above picture I mentioned the current consumption details

[Tesla DeLorean]

Yes, not really clear what the graphs show, where they are measuring, or how you've successfully separated the +VBAT_3V net from everything else you have hanging off it, including all the circuitry beyond what you've chose to show.

Have you isolated the current draw to a particular pin?

[Tesla DeLorean]

Suggests it's not idle..

Can you perhaps plot current consumption vs SCL activity pin?

Enumerate register content?

Think of things which might be salient to understanding and solving the issue.